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Study identifier: NCT06953115 Synced from ClinicalTrials.gov · July 28, 2026
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Vagal Stimulation Therapy and Preeclampsia

Condition: Gestational Hypertension · Preeclampsia  ·  Sponsor: Fundación Internacional René Mey

PhaseNA
Planned participants210
Who can joinFemale, 18 Years to no upper limit
Healthy volunteersNo

About this study

Preeclampsia is one of the most common and serious complications of pregnancy, affecting both the mother and baby. It is a condition characterized by high blood pressure and can lead to severe complications, including neurological issues and reduced blood flow to the placenta. Preeclampsia is responsible for a significant number of maternal and perinatal deaths worldwide, with an estimated 14% of maternal mortality in Mexico linked to this condition. Recent research suggests that disruptions in the body's autonomic nervous system, specifically the balance between the sympathetic and parasympathetic systems, play a role in the development of preeclampsia. The vagus nerve, which is part of the parasympathetic system, has been shown to regulate inflammation and blood pressure. Stimulating this nerve through pharmacological, magnetic, electrical, or physical therapy techniques has shown promise in preclinical models for improving blood pressure control and reducing complications associated with preeclampsia. Trigger point release therapy modulates the nervous system by reducing sympathetic activity, promoting blood vessel relaxation, lowering heart rate, and enhancing circulation. When combined with standard antihypertensive treatment, this approach may offer additional benefits for blood pressure regulation. This study aims to evaluate the effects of vagal autonomic stimulation physiotherapy using trigger point release therapy as a complementary treatment for pregnant women w…

This description comes directly from the study's public registry record.

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Locations (4)

Unidad de Investigación Biomédica 02, UMAE HE CMNO IMSSGuadalajara, Jalisco, MexicoNot Yet Recruiting
Hospital General de Zona 110, IMSSGuadalajara, Jalisco, MexicoRecruiting
Hospital General de Zona 46, IMSSGuadalajara, Jalisco, MexicoNot Yet Recruiting
Hospital General de Zona 180, IMSSTlajomulco de Zúñiga, Jalisco, MexicoNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT06953115