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Study identifier: NCT06952933 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Psychological Trauma, Post-Traumatic Stress Disorder, and Resilience in Adults With Congenital Heart Disease

Condition: Adult Congenital Heart Disease · Congenital Heart Disease · PTSD  ·  Sponsor: Dartmouth-Hitchcock Medical Center

PhaseN/A
Planned participants1000
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this study, entitled "Psychological trauma, post-traumatic stress disorder, and resilience in adults with congenital heart disease in a large population sample", is to evaluate for exposures during a lifetime with congenital heart disease that may be associated with higher likelihood of developing PTSD. Primary aim: \- Identify individual patient characteristics (medical, psychosocial, socioeconomic, etc.) that are associated with a diagnosis of PTSD. Secondary aims: * Calculate the prevalence of those meeting PTSD criteria in the ACHD population using the "gold standard" diagnostic clinician interview, while using the same data to validate a PTSD screening self-report survey in the ACHD population. * Determine the role of resilience in ACHD patients using a validated screening survey to assess its protective role toward PTSD. Hypotheses: * There are certain exposures (e.g. post-surgical pain, ICU delirium, bullying due to CHD) that are associated with a higher incidence and odds of meeting PTSD criteria. * "Gold standard" diagnostic interviews will most accurately estimate the prevalence of PTSD in ACHD which has been overestimated on prior screening-based studies, although the scope of the problem is still great. * Patients with a higher resilience score will show an association with a lower risk of PTSD.

This description comes directly from the study's public registry record.

Talk to the study team

David J Harrison, MD  ·  603-650-5724  ·  david.j.harrison@hitchcock.org

Jamie Jackson, PhD  ·  jamie.jackson2@nationwidechildrens.org

Always discuss trial participation with your own doctor first.

Locations (3)

Children's National Medical CenterWashington D.C., District of Columbia, United StatesNot Yet Recruiting
Dartmouth Hitchcock Medical CenterLebanon, New Hampshire, United StatesRecruiting
Nationwide Children's HospitalColumbus, Ohio, United StatesNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT06952933