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Study identifier: NCT06952452 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Pharmacogenomics of antiVEGF in Patients With Age-Associated Macular Degeneration (AMD)

Condition: Wet Age-related Macular Degeneration  ·  Sponsor: Parc de Salut Mar

PhasePhase 3
Planned participants630
Who can joinAll sexes, 50 Years to no upper limit
Healthy volunteersNo

About this study

This is a phase III, multicenter, randomized double-blinded clinical trial with two parallel groups (ranibizumab and bevacizumab) and an observational follow-up of patients who meet elegibility criteria and decline participation due to treatment randomization. It will be performed involving 630 eyes from patients with wet age-related macular degeneration (wAMD) diagnosis without another eye disease. This clinical trial compares the treatment response for 3 years, considering genetic variants already studied between the eyes treated with one of the first options of anti-VEGF used in patients with wAMD, (ranibizumab) and the most cost-effective anti-VEGF (bevacizumab; off-label use)

This description comes directly from the study's public registry record.

Talk to the study team

Ana Aldea  ·  +3431604900  ·  aaldea@imim.es

Melina Rojas  ·  mrojas@researchmar.net

Always discuss trial participation with your own doctor first.

Locations (4)

Hospital Universitario de CanariasSan Cristóbal de La Laguna, Santa Cruz De Tenerife, SpainRecruiting
Hospital de la Santa Creu i Sant PauBarcelona, SpainRecruiting
Hospital la EsperanzaBarcelona, SpainRecruiting
Unidad Central de Investigación Clínica y Ensayos Clínicos (UCICEC La Paz)Madrid, SpainRecruiting

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Source record: clinicaltrials.gov/study/NCT06952452