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Study identifier: NCT06949228 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Adjunctive Intra-arterial Tenecteplase Following Mechanical Thrombectomy (ALLY) II Trial

Condition: Ischemic Stroke · Acute Disease  ·  Sponsor: ProMedica Health System

PhasePhase 2/Phase 3
Planned participants132
Who can joinAll sexes, 18 Years to 85 Years
Healthy volunteersNo

About this study

The study objective is to evaluate the safety and efficacy of Intra arterial (IA) Tenecteplase (TNK) as an adjunctive therapy in acute ischemic stroke (AIS) patients with large vessel occlusions (LVO) in the anterior circulation of Internal Carotid Artery (ICA), Middle Cerebral Arteries (M1 and M2) who achieve a reperfusion grade of Modified Treatment in Cerebral Ischemia Scale (mTICI) 2b or higher post-mechanical thrombectomy using Food and Drug Administration (FDA) approved devices.

This description comes directly from the study's public registry record.

Talk to the study team

Syed Fazal Zaidi, MD  ·  (419)- 291-8027  ·  Syed.Zaidi2@utoledo.edu

Tanya Siddiqui  ·  4192913498

Always discuss trial participation with your own doctor first.

Locations (1)

ProMedica Toledo HospitalToledo, Ohio, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06949228