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Study identifier: NCT06948318 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Follow-up Study of Mezagitamab in Adults With Chronic Primary Immune Thrombocytopenia

Condition: Immune Thrombocytopenic Purpura (ITP)  ·  Sponsor: Takeda

PhasePhase 3
Planned participants150
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Primary immune thrombocytopenia (ITP) is a condition where the immune system mistakenly destroys platelets, which are cells that help stop bleeding. This leads to a lower number of platelets, making it easier to bruise or bleed. The main aim of this study is to check how safe mezagitamab is and how well it is tolerated by adults with chronic primary ITP, if given over a longer time. Other aims are to learn how effective treatment with mezagitamab is and how the body processes it (called pharmacokinetics or PK) over a longer time. Participants of the following previous mezagitamab studies will be invited to join this continuation study: TAK-079-3002 and TAK-079-1004. In this continuation study, participants will receive mezagitamab when certain protocol criteria are met. During the study, participants will visit their study clinic several times.

This description comes directly from the study's public registry record.

Talk to the study team

Takeda Contact  ·  +1-877-825-3327  ·  medinfoUS@takeda.com

Always discuss trial participation with your own doctor first.

Locations (109)

USC Norris Comprehensive Cancer Center - Keck Medicine of USCLos Angeles, California, United StatesNot Yet Recruiting
Rocky Mountain Cancer CenterDenver, Colorado, United StatesWithdrawn
Georgetown University Medical Center - Lombardi Comprehensive Cancer CenterWashington D.C., District of Columbia, United StatesNot Yet Recruiting
Emory UniversityAtlanta, Georgia, United StatesNot Yet Recruiting
The University of IowaIowa City, Iowa, United StatesNot Yet Recruiting
University Of Louisville Brown Cancer CenterLouisville, Kentucky, United StatesNot Yet Recruiting
Massachusetts General HospitalBoston, Massachusetts, United StatesRecruiting
University of Massachusetts Chan Medical SchoolWorcester, Massachusetts, United StatesNot Yet Recruiting
Duke University HospitalDurham, North Carolina, United StatesNot Yet Recruiting
East Carolina UniversityGreenville, North Carolina, United StatesNot Yet Recruiting
Oregon Health & Science UniversityPortland, Oregon, United StatesNot Yet Recruiting
Perelman Center for Advanced Medicine (PCAM) Hospital of The University of Pennsylvania Penn Blood Disorders ProgramPhiladelphia, Pennsylvania, United StatesNot Yet Recruiting

+ 97 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06948318