Condition: Refractory Lupus Nephritis · Systemic Sclerosis · Primary Sjogren's Syndrome Combined With Pulmonary Hypertension · Sponsor: Beijing GoBroad Hospital
This is a single-center, open-label, non-randomized, single-arm clinical trial. Patients with refractory lupus neritis (SLE-LN), systemic sclerosis (SSc), and primary Sjogren syndrome combined with pulmonary artery hypertension (pSS-PAH) receive CD19-BCMA CAR T cell therapy. The primary objective is to prospectively assess the safety of CD19-BCMA CAR T cell therapy in patients with SLE-LN, SSc, and pSS-PAH. The primary endpoint is the type and incidence of dose-limiting toxicity (DLT) within 28 days after CD19-BCMA CAR T cell infusion.
This description comes directly from the study's public registry record.
ZHOU · 86+18511772961 · zhousn@gobroadhealthcare.com
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| 北京高博医院 | Beijing, China,Beijing, China | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06947460