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Study identifier: NCT06947044 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Biomarkers in Patients With Anemia-Induced Thrombocytopenic Bleeding

Condition: Acute Leukemia · Acute Myeloid Leukemia (AML) · Acute Lymphocytic Leukaemia  ·  Sponsor: Donald Arnold

PhaseNA
Planned participants60
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This pilot study aims to gather preliminary evidence on how different hemoglobin levels impact blood biomarkers related to bleeding. The feasibility of conducting a future larger clinical trial will also be assessed. Red blood cell transfusions are part of the standard of care for patients with leukemia. This study evaluates two transfusion strategies: one that maintains hemoglobin levels above the standard-of-care threshold, reflecting current routine practice; and another that maintains hemoglobin levels above 110 g/L, which is closer to the normal hemoglobin range. The normal hemoglobin range is 120-160 g/L for females and 140-180 g/L for males. Raising hemoglobin levels closer to normal values may reduce bleeding risk.

This description comes directly from the study's public registry record.

Talk to the study team

Dimpy Modi  ·  905-525-9140  ·  modid1@mcmaster.ca

Always discuss trial participation with your own doctor first.

Locations (1)

Juravinski HospitalHamilton, Ontario, CanadaRecruiting

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Source record: clinicaltrials.gov/study/NCT06947044