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Study identifier: NCT06946901 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

The Safety and Effectiveness of Hyperthermic Intraperitoneal Chemotherapy Combined With Intravenous Chemotherapy for Peritoneal Metastatic Pancreatic Cancer, a Phase II Clinical Trial

Condition: Hyperthermic Intraperitoneal Chemotherapy · Peritoneal Metastatic Pancreatic Cancer  ·  Sponsor: Shanghai Zhongshan Hospital

PhasePhase 2
Planned participants90
Who can joinAll sexes, 18 Years to 80 Years
Healthy volunteersNo

About this study

The goal of this clinical trial is to evaluate the effectiveness and safety of hyperthermic intraperitoneal chemotherapy combined with intravenous chemotherapy in peritoneal metastatic pancreatic cancer. The main question it aims to answer are: (1) Does this combined approach increase 1-year survival rates? and (2) What is the safety profile of this treatment regimen? Participants will: undergo baseline imaging and surgical exploration to confirm peritoneal metastasis, receive two cycles of intraperitoneal cisplatin HIPEC (70mg/m²) postoperatively, followed by systemic AG chemotherapy (nab-paclitaxel plus gemcitabine), with treatment adjustments based on regular imaging assessments and multidisciplinary team (MDT) recommendations.

This description comes directly from the study's public registry record.

Talk to the study team

Wenquan Wang, Dr  ·  86 13701874954  ·  wang.wenquan@zs-hospital.sh.cn

Always discuss trial participation with your own doctor first.

Locations (2)

The Second Xiangya Hospital of Central South UniversityChangsha, Hunan, ChinaNot Yet Recruiting
Zhongshan Hospital, Fudan UniversityShanghai, Shanghai Municipality, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06946901