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Study identifier: NCT06946550 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Non-Ablative Laser to Treat Scarring Alopecia With Hair Follicle Gene Expression Analysis

Condition: Scarring Alopecia  ·  Sponsor: Montefiore Medical Center

PhaseNA
Planned participants5
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersYes

About this study

The goal of this clinical trial is to evaluate the effectiveness of a non-ablative 1470 nm laser in treating scarring alopecia in adults. The study will also investigate the biochemical molecular pathways involved in laser therapy by analyzing hair follicle gene expression before and after laser treatment. The main questions it aims to answer are: 1. Does a non-ablative laser work to effectively treat scarring alopecia? 2. What molecular pathways are associated with the laser's effects on hair follicles in scarring alopecia? Participants with scarring alopecia will: * Receive 3 laser treatments, spaced 1 month apart (Month 1, Month 2, Month 3), and attend 5 follow-up visits (Month 4, Month 6, Month 9, Month 12 and Month 15) * Have hair follicle samples collected via hair plucking of 10 hairs prior to the start and 1-month post-completion of laser treatments for gene expression analysis of inflammatory and fibrosis pathways implicated in scarring alopecia. Hair samples will be de-identified and kept anonymous. * Fill out questionnaires at each visit * Keep a diary of any side effects from laser treatments

This description comes directly from the study's public registry record.

Talk to the study team

Anika Jallorina, BS  ·  618-704-8716  ·  ajallorina@montefiore.org

Always discuss trial participation with your own doctor first.

Locations (1)

Montefiore Einstein Advanced CareElmsford, New York, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06946550