Condition: BPH (Benign Prostatic Hyperplasia) · Lower Urinary Track Symptoms · Sponsor: Beth Israel Deaconess Medical Center
SRD5A2 is a critical enzyme for prostatic development and growth, and the SRD5A2 inhibitor, finasteride, is used to treat benign prostatic hyperplasia (BPH). SRD5A2 is absent in 30% of normal adult men, which explains the resistance of a subset of patients to this commonly prescribed drug. This project proposes new combination therapies (5-ARI+raloxifene) and evaluates novel non-invasive biomarkers, based on alternative pathways that lead to prostatic enlargement.
This description comes directly from the study's public registry record.
Yulia Mulugeta · 617-632-8890 · ymuluget@bidmc.harvard.edu
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| Beth Israel Deaconess Medical Center | Boston, Massachusetts, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06944145