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Study identifier: NCT06943846 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Platelet-Rich Fibrinogen in Extraction Socket Healing of the Aged

Condition: Edentulism  ·  Sponsor: University of Nebraska

PhaseNA
Planned participants12
Who can joinAll sexes, 14 Years to 80 Years
Healthy volunteersNo

About this study

The purpose of this study is to better understand oral wound healing in the aged participant following placement of platelet-rich fibrinogen (PRF). In this study, 12 participants requiring a posterior tooth extraction will be enroll: 6 participants aged 14-18, 6 participants aged 50-80. All will undergo a posterior tooth extraction with a small tissue specimen taken from the extraction site. Half of the participants will also have their blood drawn and platelet-rich fibrinogen placed in the extraction socket. Participants will return in 2 weeks for suture removal and another soft tissue sample. Participants will return at 3 months for a final post-operative radiograph. All soft tissue samples will undergo immunofluorescence.

This description comes directly from the study's public registry record.

Talk to the study team

Amy C Killeen, DDS, MS  ·  402-472-7848  ·  akilleen@unmc.edu

Always discuss trial participation with your own doctor first.

Locations (1)

University of Nebraska Medical Center College of DentistryLincoln, Nebraska, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06943846