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Study identifier: NCT06943820 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

AK129 Combination Therapy for Advanced Solid Tumors

Condition: Non-small Cell Lung Cancer Stage IIIB/IV · Head and Neck Squamous Cell Carcinoma (HNSCC) · Colorectal Adenocarcinoma  ·  Sponsor: Akeso

PhasePhase 1/Phase 2
Planned participants230
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

This is an open, multicenter phase Ib/II clinical study. The goal of this study is to confirm the Phase II recommended dose (RP2D) of AK129 combinations for advanced solid tumors and evaluate the safety and efficacy of AK129 combinations for non-small cell lung cancer (NSCLC), head and neck squamous cell carcinoma (HNSCC), colorectal adenocarcinoma (CRC), and other advanced solid tumors.

This description comes directly from the study's public registry record.

Talk to the study team

Wenting Li,M.D.  ·  +86(0760)89873999  ·  clinicaltrials@akesobio.com

Hongxu Liu,M.D.  ·  Hongxuliu@qq.com

Always discuss trial participation with your own doctor first.

Locations (1)

Liaoning Cancer HospitalShenyang, Liaoning, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06943820