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Study identifier: NCT06942039 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Pilot Study of IT Topotecan and Maintenance Chemotherapy for HR-EBTs in Children < 6 Years, Post Consolidation

Condition: CNS Embryonal Tumor · CNS, Medulloblastoma · Atypical Teratoid Rhabdoid Tumor  ·  Sponsor: C17 Council

PhaseEARLY_Phase 1
Planned participants15
Who can joinAll sexes, N/A to 6 Years
Healthy volunteersNo

About this study

Pilot study to determine feasibility of adding intrathecal chemotherapy and maintenance therapy after high dose chemotherapy for treatment of newly diagnosed HR-EBTs in patients less than 6 years of age.

This description comes directly from the study's public registry record.

Talk to the study team

Sylvia Cheng  ·  416-813-7654  ·  sylvia.cheng@cw.bc.ca

C17 Council  ·  DECRYPT-BABYBRAIN@C17.ca

Always discuss trial participation with your own doctor first.

Locations (12)

Alberta Children's HospitalCalgary, Alberta, CanadaRecruiting
BC Children's HospitalVancouver, British Columbia, CanadaRecruiting
CancerCare Manitoba (CCMB)Winnipeg, Manitoba, CanadaRecruiting
IWK Health CentreHalifax, Nova Scotia, CanadaNot Yet Recruiting
McMaster Children's HospitalHamilton, Ontario, CanadaRecruiting
London Health Sciences CentreLondon, Ontario, CanadaRecruiting
CHU Sainte-JustineMontreal, Quebec, CanadaRecruiting
Montreal Children's Hospital (McGill)Montreal, Quebec, CanadaNot Yet Recruiting
CHU de Québec-Université LavalQuébec, Quebec, CanadaRecruiting
Centre hospitalier universitaire de Sherbrooke (CHUS)Sherbrooke, Quebec, CanadaRecruiting
Stollery Children's HospitalEdmonton, CanadaRecruiting
The Hospital for Sick ChildrenToronto, CanadaRecruiting

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Source record: clinicaltrials.gov/study/NCT06942039