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Study identifier: NCT06941025 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Maternal and Postnatal Outcomes Study (MOS): A Global Observational Registry Assessing the Safety of Elfabrio® in Women With Fabry Disease and Their Infants During Pregnancy and Breastfeeding

Condition: Fabry Disease · Pregnancy · Pregnancy Complications  ·  Sponsor: Chiesi Farmaceutici S.p.A.

PhaseN/A
Planned participants10
Who can joinFemale, N/A to no upper limit
Healthy volunteersNo

About this study

The goal of this observational registry is to evaluate the safety and outcomes of pregnancy and lactation in women with Fabry disease who are exposed to pegunigalsidase alfa within 30 days prior to conception and/or during pregnancy and lactation. The main objectives are to: * Assess pregnancy outcomes, including maternal and infant health. * Evaluate the occurrence of congenital malformations and other neonatal outcomes. This is a global, decentralized, single-arm, prospective and retrospective registry planned to enroll participants over a 10-year period. Eligible patients may be enrolled by their physician or may self-enroll, where permitted by local regulations. Data will be collected through a secure web-based platform, allowing patients and physicians to enter information via electronic case report forms (eCRFs). Pregnancy and clinical outcomes will be documented throughout pregnancy and up to 12 months post-birth. Data from self-enrolled patients will be confirmed by their primary care or attending physician. This registry is observational and does not impact clinical care or treatment decisions.

This description comes directly from the study's public registry record.

Talk to the study team

Chiesi Clinical Trial  ·  +3905212791  ·  clinicaltrials_info@chiesi.com

Always discuss trial participation with your own doctor first.

Locations (5)

No physical study sites - Decentralized, web-based registryWashington D.C., District of Columbia, United StatesRecruiting
No physical study sites - Decentralized, web-based registryBerlin, GermanyRecruiting
No physical study sites - Decentralized, web-based registryRome, ItalyRecruiting
No physical study sites - Decentralized, web-based registryMadrid, SpainRecruiting
No physical study sites - Decentralized, web-based registryLondon, United KingdomNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT06941025