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Study identifier: NCT06940596 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Exclude or Expose in Irritable Bowel Syndrome: What Works for Whom and How?

Condition: Irritable Bowel Syndrome (IBS) · Intestinal Diseases · Gastrointestinal Disease  ·  Sponsor: University of Melbourne

PhaseNA
Planned participants235
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This research project will assess how two treatments for irritable bowel syndrome (one dietary and one behavioral) work and for whom. This will be done by assessing moderators (what treatment works for who and in what context) and mediators (how treatment works). Investigators will also assess how the diet and behavioral treatments affect IBS symptoms during treatment. Participants will be randomized to either: i. A FODMAP diet online program that focuses on modifying the consumption of foods high or moderate in fermentable carbohydrates (FODMAPS) to manage IBS symptoms. or, ii. An Exposure-based Cognitive Behavioral Therapy (E-CBT) online program for IBS that focuses on changing symptom-related behaviors which are known to worsen IBS symptoms.

This description comes directly from the study's public registry record.

Talk to the study team

Jessica Biesiekierski, A/Prof  ·  +61 499 272 673  ·  jessica.biesiekierski@unimelb.edu.au

Jacqueline L Anderson, APD  ·  jacquia@student.unimelb.edu.au

Always discuss trial participation with your own doctor first.

Locations (1)

University of MelbourneMelbourne, Victoria, AustraliaRecruiting

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Source record: clinicaltrials.gov/study/NCT06940596