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Study identifier: NCT06939348 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Ultrasound Stimulation for Patients in a Disorder of Consciousness

Condition: Consciousness Disorders · Disorders of Consciousness Due to Severe Brain Injury  ·  Sponsor: University of California, Los Angeles

PhaseNA
Planned participants60
Who can joinAll sexes, 18 Years to 79 Years
Healthy volunteersNo

About this study

The overall aim of this study is to develop an intervention that can help recovery in patients surviving severe brain injury but failing to fully recover. In particular, this multicenter project aims to (1) establish short-term efficacy of tFUS as a therapeutic to promote recovery in patients with prolonged DoC as compared to sham treatment, (2) establish dose-related safety and efficacy of tFUS as a therapeutic intervention in prolonged DoC patients and (3) explore preliminary predictors and biomarkers of susceptibility and response to thalamic sonication.

This description comes directly from the study's public registry record.

Talk to the study team

Martin M Monti, PhD  ·  310-825-8546  ·  monti@psych.ucla.edu

Caroline Schnakers, PhD  ·  (909) 596-7733  ·  cschnakers@casacolina.org

Always discuss trial participation with your own doctor first.

Locations (4)

The Regents of the University of California, Los AngelesLos Angeles, California, United StatesRecruiting
Casa Colina Hospital and Centers for HealthcarePomona, California, United StatesRecruiting
Massachusetts General Hospital (The General Hospital Corp.)Boston, Massachusetts, United StatesRecruiting
Spaulding Rehabilitation Hospital Corporation, Inc.Charlestown, Massachusetts, United StatesNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT06939348