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Study identifier: NCT06937944 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Efficacy and Safety of Recombinant Botulinum Toxin Type A (Eveotox) for Injection to Treat Moderate to Severe Glabellar Lines

Condition: Moderate to Severe Glabellar Lines  ·  Sponsor: JHM BioPharma (Tonghua) Co. , Ltd.

PhasePhase 3
Planned participants669
Who can joinAll sexes, 18 Years to 65 Years
Healthy volunteersNo

About this study

This is a Phase 3 clinical study to evaluate the efficacy, safety, and immunogenicity of single/repeated injections of Eveotox in the treatment of moderate to severe glabellar lines. The study consists of Study Part 1 (randomized double-blind controlled study) and Part 2 (open-label study). Part I is a multicenter, randomized, double-blind, single-injection, active-controlled and placebo-controlled study to evaluate the efficacy, safety, and immunogenicity of Eveotox in the treatment of moderate to severe glabellar lines; Part 2 is an open-label study to evaluate the efficacy, safety, and immunogenicity of repeated injections of Eveotox in the treatment of moderate to severe glabellar lines.

This description comes directly from the study's public registry record.

Talk to the study team

Danhua Lin  ·  15811460241  ·  danhua.lin@jhm-biopharma.com

Lei Wang  ·  lei.wang@jhm-biopharma.com

Always discuss trial participation with your own doctor first.

Locations (15)

Peking Union Medical College HospitalBeijing, Beijing Municipality, ChinaRecruiting
Peking University First HospitalBeijing, Beijing Municipality, ChinaRecruiting
Peking University Third HospitalBeijing, Beijing Municipality, ChinaRecruiting
The First Affiliated Hospital of Chongqing Medical UniversityChongqing, Chongqing Municipality, ChinaRecruiting
The First Affiliated Hospital of Jinan UniversityGuangzhou, Guangdong, ChinaRecruiting
The Third Affiliated Hospital of Sun Yat-sen UniversityGuangzhou, Guangdong, ChinaRecruiting
The First Hospital of Hebei Medical UniversityShijiazhuang, Hebei, ChinaRecruiting
The Third Xiangya Hospital of Central South UniversityChangsha, Hunan, ChinaRecruiting
The Affiliated Hospital of Xuzhou Medical UniversityXuzhou, Jiangsu, ChinaRecruiting
Huashan Hospital, Fudan UniversityShanghai, Shanghai Municipality, ChinaRecruiting
Xianyang Hospital of Yan'an UniversityXianyang, Shanxi, ChinaRecruiting
West China Hospital, Sichuan UniversityChengdu, Sichuan, ChinaRecruiting

+ 3 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06937944