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Study identifier: NCT06937853 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Effect of Genetic Polymorphisms on Response to Preoperative NSAIDs in Endodontic Postoperative Pain Management

Condition: Postoperative Pain  ·  Sponsor: Ataturk University

PhaseNA
Planned participants200
Who can joinAll sexes, 18 Years to 65 Years
Healthy volunteersYes

About this study

This study aims to evaluate the influence of genetic polymorphisms on the effectiveness of preoperative non-steroidal anti-inflammatory drugs (NSAIDs) in managing postoperative pain following endodontic treatment. Participants will receive standard preoperative NSAIDs before undergoing root canal therapy, and their pain responses will be assessed. Genetic analysis will be performed to investigate possible associations between drug response and individual gene variations. The study seeks to improve personalized approaches in endodontic pain management.

This description comes directly from the study's public registry record.

Talk to the study team

Ertugrul Karatas, Prof. Dr.  ·  +905337080730  ·  dtertu@windowslive.com

Melike Kahramanlar, Postgraduate Student  ·  +905357992872  ·  kahramanlarmelike@gmail.com

Always discuss trial participation with your own doctor first.

Locations (1)

Ataturk University, Faculty of Dentistry, Department of EndodonticsErzurum, Erzurum, Turkey (Türkiye)Recruiting

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Source record: clinicaltrials.gov/study/NCT06937853