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Study identifier: NCT06936189 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Prospective Trial of IVL for Calcified Carotid Lesions(CREATE Trial)(Extended Follow-Up)

Condition: Carotid Artery Stenosis  ·  Sponsor: Shanghai Bluesail Boyuan Medical Technology Co., Ltd.

PhaseN/A
Planned participants204
Who can joinAll sexes, 18 Years to 80 Years
Healthy volunteersNo

About this study

Purpose: To assess the long-term safety and efficacy of the intravascular lithotripsy system for pre-treatment of calcified carotid artery stenosis. Design: Prospective, multicenter, single-arm study with an extended follow-up period. Sample Size: 204 participants (based on the final number of cases enrolled in the registration trial). Endpoints: Primary: Surgical success rate (residual stenosis \<30% after stenting). Secondary: Target lesion re-narrowing rate, target lesion revascularization rate, MAE rate, ipsilateral stroke rate, and MACCE rate at 3 and 6 months postoperatively. Follow-Up: Participants will be followed up at 3 months ±15 days and 6 months ±30 days postoperatively. Inclusion criteria: All patients participating in this extended follow-up period are sourced from the registered clinical trial. Ethics and Consent: The trial will be conducted in accordance with the Helsinki Declaration and Chinese regulations. Informed consent will be obtained from all participants or their legal guardians. Sponsor: Shanghai Lanfan Boyuan Medical Technology Co., Ltd. Principal Investigator: Professor Huo Xiaochuan, Beijing Anzhen Hospital.

This description comes directly from the study's public registry record.

Talk to the study team

Xiaochuan Huo  ·  010-64412431  ·  huoxiaochuan@126.com

Always discuss trial participation with your own doctor first.

Locations (1)

Beijing Anzhen HospitalBeijing, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06936189