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Study identifier: NCT06935188 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Dalpicilib Plus Cetuximab Compared With Cetuximab Alone in HPV-negative, Anti-PD-1-resistant R/M HNSCC

Condition: Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma  ·  Sponsor: Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University

PhasePhase 2
Planned participants98
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

This study is a single center, randomized controlled, prospective phase II clinical trial to evaluate the efficacy and safety of cetuximab combined with dalpicilib compared to cetuximab monotherapy in patients with HPV-negative, anti-PD-1-resistant recurrent or metastatic head and neck squamous cell carcinoma. The participants would receive cetuximab combined with dalpicilib or cetuximab monotherapy until termination criteria are met.

This description comes directly from the study's public registry record.

Talk to the study team

Guoxin Ren  ·  13916948812  ·  renguoxincn@sina.com

Always discuss trial participation with your own doctor first.

Locations (1)

the Ninth People's Hospital Affiliated to Shanghai Jiao Tong University School of MedicineShanghai, Shanghai Municipality, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06935188