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Study identifier: NCT06934421 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Revised Targets for Knee Radiofrequency Ablation

Condition: Osteoarthritis Knee Pain  ·  Sponsor: Centro Hospitalar Universitario do Algarve

PhaseN/A
Planned participants60
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This research team is doing a study to learn more about a new way to treat long-term knee pain caused by joint damage. They are using a treatment called radiofrequency ablation (RFA). This is a procedure where doctors use heat to stop certain nerves from sending pain signals. In this study, doctors will use ultrasound to guide a small needle to nerves around the knee, called genicular nerves. Then, they will apply heat to those nerves using radiofrequency energy to help reduce pain. The team created this new method based on recent studies of knee anatomy. They want to find out if this method can safely reduce pain and help people with knee joint damage move better. The study includes people who have moderate to severe knee damage and still have pain after trying medicine, physical therapy, or joint injections. Each person in the study will have the treatment once. The research team will follow each person for two years. During this time, people in the study will answer simple questions about their knee pain and how it affects their daily life. The researchers will collect this information before the treatment and several times after it. One week after the procedure, the team will call each person to ask how they are feeling and check for any side effects. Possible benefits of the study include less knee pain and easier movement. Possible risks include pain during the procedure, bruising, swelling, or short-term worsening of pain. Rare risks include nerve problems, weaknes…

This description comes directly from the study's public registry record.

Talk to the study team

Manuel Tomás Farinha Caroço, Medical Doctor  ·  +351968010683  ·  farinhacaroco@gmail.com

Giovanni Leoni, Medical Doctor  ·  +39 328 613 3631  ·  gioleoni95@gmail.com

Always discuss trial participation with your own doctor first.

Locations (2)

Serviço de Medicina Física e de Reabilitação - Hospital de Faro - Unidade Local de Saúde do AlgarveFaro, PortugalRecruiting
Serviço de Medicina Física e de Reabilitação - Hospital de São Francisco Xavier - Unidade Local de Saúde de Lisboa OcidentalLisbon, PortugalNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT06934421