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Study identifier: NCT06933407 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Elastographic Assessment of Suburethral Tissue in Continent and Incontinent Women

Condition: Urinary Incontinence · Urinary Incontinence, Stress · Urinary Incontinence (UI)  ·  Sponsor: Szeged University

PhaseN/A
Planned participants80
Who can joinFemale, 18 Years to 99 Years
Healthy volunteersYes

About this study

Strain elastography (SE) will be utilized as a non-invasive imaging technique to evaluate tissue elasticity and biomechanical properties in women with stress urinary incontinence (SUI) and in continent controls. The primary aim is to determine whether SE can detect differences in paraurethral tissue stiffness between these groups. Given the established role of tissue elasticity in the pathophysiology of SUI, SE will be investigated as a potential diagnostic tool in urogynecological evaluations. This prospective cohort study will be conducted at a tertiary referral center. All participants will undergo introital two-dimensional (2D) ultrasound in the midsagittal plane at rest. SE will be performed in three predefined suburethral regions of interest (ROIs): * internal urethral orifice (IUO) level * midurethra (MU) level * external urethral orifice (EUO) level The adipose layer (AL) between the external urethral meatus and the pubic symphysis will serve as the reference tissue, representing the softest anatomical structure in the region. Descriptive and comparative statistical analyses will be conducted to assess differences in paraurethral tissue stiffness between the study groups. It is hypothesized that SE will be able to detect differences in paraurethral tissue elasticity, with SUI being associated with increased tissue compliance. The study also aims to determine whether SE can reliably distinguish between varying degrees of tissue stiffness in women with SUI and cont…

This description comes directly from the study's public registry record.

Talk to the study team

Lóránt Csákány, Dr.  ·  +36305895619  ·  md.csakany@gmail.com

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Locations (1)

University of szegedSzeged, HungaryRecruiting

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Source record: clinicaltrials.gov/study/NCT06933407