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Study identifier: NCT06933212 Synced from ClinicalTrials.gov · July 28, 2026
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Effect of the Mediterranean Diet in Patients Affected by CADASIL and Cerebral Amyloid Angiopathy.

Condition: Cerebral Amyloid Angiopathy · CAA - Cerebral Amyloid Angiopathy  ·  Sponsor: Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta

PhaseN/A
Planned participants86
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The study is divided into two phases: Phase 1 (observational) and Phase 2 (dietary intervention). The goal of Phase 1 is to assess the nutritional status and dietary habits of two cohorts of patients with CADASIL and CAA. A specific aim is to evaluate adherence to the Mediterranean Diet. The objectives include analyzing patients' nutritional status, lean and fat mass, basal metabolism, and total energy expenditure. It also aims to assess the relationship between adherence to the Mediterranean Diet and the onset of stroke and cognitive decline, as well as examine stroke severity (ischemic or hemorrhagic) and its association with Mediterranean Diet adherence (MEDAS questionnaire). Additionally, the study will explore the link between diet adherence and cognitive deficits, and measure changes in biological and anthropometric parameters as a result of adopting the Mediterranean Diet. Phase 2 is an interventional dietary study designed to evaluate the effects of the Mediterranean Diet, enriched with either extra virgin olive oil or walnuts, on stroke incidence and cognitive decline in patients with CAA and CADASIL.

This description comes directly from the study's public registry record.

Talk to the study team

Anna Bersano, MD  ·  02 2394.3062  ·  anna.bersano@istituto-besta.it

Always discuss trial participation with your own doctor first.

Locations (1)

Fondazione IRCCS Istituto Neurologico Carlo BestaMilan, ItalyRecruiting

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Source record: clinicaltrials.gov/study/NCT06933212