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Study identifier: NCT06933173 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

RCT of Mind-body in Long COVID and Myalgic Encephalomyelitis

Condition: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome  ·  Sponsor: University of Alberta

PhaseNA
Planned participants200
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

We are studying the effect of a mind-body treatment for people with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) with or without Long COVID (LC). Our team recognizes that ME/CFS and Long COVID are serious, debilitating, biomedical conditions. ME/CFS can affect many different parts of the body, such as the nervous system, immune system, and metabolism. It is hypothesized that central sensitization (i.e., when nerves get too excited) may influence these complex conditions and may make symptoms worse. This study explores a mind-body program called the Dynamic Neural Retraining System™, or DNRS™. Mind-body interventions (MBIs) focus on how the brain, mind, body, and behaviour interact to improve health and well-being. These techniques help people become more aware of themselves, take better care of their health, and boost mood, quality of life, and coping skills. MBIs use the brain's ability to change (neuroplasticity) by reinforcing certain thoughts, feelings, or behaviours that support changes in biology and function. MBIs may influence physical health by affecting how the brain and body communicate through chemicals such as hormones and neurotransmitters. Objective fMRI evidence shows that practising MBIs can change brain structure and function. This makes MBIs a potential good fit for people with chronic illnesses like ME/CFS and LC, which involve complex interactions between the brain, immune system, and hormones. There is no rigorous peer-reviewed evidenc…

This description comes directly from the study's public registry record.

Talk to the study team

MILES RCT team  ·  780-680-8907  ·  rctmiles@ualberta.ca

Always discuss trial participation with your own doctor first.

Locations (3)

Peter Lougheed HospitalCalgary, Alberta, CanadaRecruiting
University of Alberta Hospital/Kaye Edmonton ClinicEdmonton, Alberta, CanadaRecruiting
Women's College HospitalToronto, Ontario, CanadaRecruiting

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Source record: clinicaltrials.gov/study/NCT06933173