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Study identifier: NCT06932458 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Clinical Trial of Primary Retroperitoneal Lymph Node Dissection in Patients With Testicular Seminoma With Limited Retroperitoneal Metastases

Condition: Testicular Cancer  ·  Sponsor: Western University, Canada

PhasePhase 2
Planned participants30
Who can joinMale, 18 Years to no upper limit
Healthy volunteersNo

About this study

Testicular cancer represents 1% of adult neoplasms and is the most common solid malignancy in young men. At diagnosis, approximately 90% of cases are germ cell tumours (GCT), categorised as either seminoma (55-60%) or non-seminoma types (40-45%). For many years, the management of patients with CS IIA/B seminoma and retroperitoneal lymph node involvement ≤ 3 cm are eligible for treatment with either radiotherapy or chemotherapy Despite high cure rates for CS II seminoma (approximately 90%) with chemotherapy or radiotherapy, concerns persist regarding short and long-term treatment-related toxicities (such as increased risks of cardiovascular disease and secondary malignancies As such, an alternative strategy which has been explored in this study is the role of RPLND for the management of these patients

This description comes directly from the study's public registry record.

Talk to the study team

Kaydee Connors  ·  519-685-8500  ·  Kaydee.Connors@lhsc.on.ca

Always discuss trial participation with your own doctor first.

Locations (1)

London Health Sciences CentreLondon, Ontario, CanadaRecruiting

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Source record: clinicaltrials.gov/study/NCT06932458