Condition: Neuro-PASC · Long COVID · Sponsor: VA Office of Research and Development
Mental health symptoms, including cognitive impairment ("brain fog"), following COVID-19 are of great concern to Veterans. This research seeks to advance understanding of the long-term effects of COVID-19 on neuropsychiatric and neurological functions, identifying clinically relevant biomarkers and directions for developing and testing therapeutic interventions. To accomplish these objectives the investigators are conducting a longitudinal study at two VA medical centers to: 1) assess and monitor cognitive function and psychiatric symptoms in Veterans post-COVID; 2) evaluate biomarkers of inflammation and signaling pathways associated with viral infection and neuropsychiatric function; and 3) integrate neuropsychiatric and neurological findings with biological data to identify biomarkers and clinical endpoints associated with disease progression or severity, as well as those for promoting brain repair and attenuating those symptoms.
This description comes directly from the study's public registry record.
Jennifer M Loftis, MA PhD · (503) 220-8262 · Jennifer.Loftis2@va.gov
Emily R Sano, MA · (503) 220-8262 · emily.sano@va.gov
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| VA Portland Health Care System, Portland, OR | Portland, Oregon, United States | Recruiting |
| James H. Quillen VA Medical Center, Mountain Home, TN | Mountain Home, Tennessee, United States | Not Yet Recruiting |
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Source record: clinicaltrials.gov/study/NCT06932237