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Study identifier: NCT06931574 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Double Kissing-crush vs Controlled Balloon-crush Techniques For Complex Coronary Bfurcation Lesions

Condition: Coronary Arterial Disease (CAD) · Percutaneous Coronary Intervention (PCI) · Bifurcation Coronary Disease  ·  Sponsor: Istanbul Mehmet Akif Ersoy Educational and Training Hospital

PhaseN/A
Planned participants300
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The Crush technique for coronary bifurcation lesions has evolved significantly since its introduction to the literature by Colombo et al. in 2003, with several iterations, including double kissing balloon inflation. The main disadvantage of the historical Crush technique is the low success rate of the final kissing balloon inflation. An improvement came with the introduction of double kissing crush stenting aiming for the shorter protrusion and kissing balloon dilation performed before and after main branch stent implantation. The double kissing crush provides a significant reduction in major adverse cardiovascular events compared to Provisional stenting, Crush, and Culotte techniques. Recently, a novel modified mini-crush technique (controlled balloon-crush) has been introduced to the literature and is one of the most up-to-date crush techniques. The main advantage of this technique over the contemporary mini-crush technique is that the side branch can be easily rewired, and the 1:1 size non-compliant balloon can easily pass through the crushed stent structure in the ostial part of the side branch. The basic rationale of this is that the crushing of the side branch stent is done in a more controlled manner (by slowly deflation of the side branch stent balloon), and this causes less disruption of the stent cells. To date, no data compares the mid-term outcomes of double kissing crush and controlled balloon-crush stenting techniques in patients with complex coronary bifurcatio…

This description comes directly from the study's public registry record.

Talk to the study team

Fatih Uzun, Professor  ·  902126922000  ·  fatihuzun28@gmail.com

Abdullah Doğan, MD

Always discuss trial participation with your own doctor first.

Locations (2)

Istanbul Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Training and Research HospitalIstanbul, Turkey (Türkiye)Recruiting
Istanbul Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Training and Research HospitalIstanbul, Turkey (Türkiye)Recruiting

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Source record: clinicaltrials.gov/study/NCT06931574