Condition: Non-small Cell Lung Cancer · Minimal Residual Disease · Adaptive Treatment · Sponsor: Peking University People's Hospital
The goal of this study is to develop new techniques for minimal residual disease(MRD) monitoring and to confirm the efficacy and safety of MRD-guided postoperative management for early stage non-small cell lung cancer. The main questions this study aims to answer are: * How to develop multi-omics-based high-sensitivity detection methods to accurately capture MRD and monitor postoperative recurrence in lung cancer? * Is adaptive treatment guided by ctDNA-MRD for lung cancer patients superior to traditional clinical management and effectively improves survival? * Do heterogeneous patient populations (grouped by stages, histopathological subtypes, driver mutations, and treatment histories) show differences in effects under ctDNA-MRD guided postoperative management strategies?
This description comes directly from the study's public registry record.
Kezhong Chen, MD · +86-010-88325983 · mdkzchen@163.com
Xiaoqiu Yuan · +86-010-88325983 · YuanXQ_pkuphxw@foxmail.com
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| Peking University People's Hospital | Beijing, Beijing Municipality, China | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06930807