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Study identifier: NCT06929507 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Impact of Intravitreal Faricimab on Renal Function in Diabetic Patients

Condition: Renal Function Disorder · Diabetic Macular Edema (DME) · Neovascular Age Related Macular Degeneration  ·  Sponsor: University Hospital, Alexandroupolis

PhaseNA
Planned participants60
Who can joinAll sexes, N/A to no upper limit
Healthy volunteersNo

About this study

This study aims to investigate the impact of intravitreal injection of anti-vascular endothelial growth factor (anti VEGF) Faricimab on renal function of diabetic patients. Faricimab is a new anti-VEGF drug which inhibits both VEGF-A and Ang-2 and it is used for the treatment of diabetic macular edema and neovascular age related macular degeneration. It is known that previous anti-VEGF agents has systematic absorption and may cause deterioration in renal function of the patients. However, the effect of Faricimab on kidney function has not been investigated yet. Taking into account that Ang-2 has destructive effect on kidneys, the investigation of the effect of its inhibition in diabetic patients who have already renal function deterioration may provide a valuable information in scientific community.

This description comes directly from the study's public registry record.

Talk to the study team

Asli Perente, Dr  ·  +306951577205  ·  asli_perende-90@hotmail.com

Always discuss trial participation with your own doctor first.

Locations (2)

University Hospital of AlexandroupolisAlexandroupoli, Evros, GreeceRecruiting
University Hospital of AlexandroupolisAlexandroupoli, GreeceCompleted

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Source record: clinicaltrials.gov/study/NCT06929507