Condition: Thrombotic Thrombocytopenic Purpura, Acquired · Sponsor: Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
This study aims to investigate whether genetic variation in the TNFAIP3 locus is associated with immune-mediated thrombotic thrombocytopenic purpura (iTTP), and whether such association is mediated by decreased expression of A20 (TNFAIP3). The study includes a case-control design to assess genotype-expression association and a cohort study to evaluate clinical outcomes such as disease relapse.
This description comes directly from the study's public registry record.
Ilaria Mancini, PhD · +390255035414 · ilaria.mancini@guest.unimi.it
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| Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico | Milan, Italy | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06928233