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Study identifier: NCT06926543 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Postoperative Radiotherapy in Breast Cancer- Concurrent or Sequential With Chemotherapy

Condition: Invasive Breast Cancer · Stage III Breast Cancer · Stage IIB Breast Cancer  ·  Sponsor: Dr. Tabassum Wadasadawala

PhasePhase 3
Planned participants858
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This clinical research aims to determine if concurrent chemotherapy and radiation therapy is more effective than sequential chemotherapy and radiation therapy for patients with stage IIB-III breast cancer. It seeks to answer the following key questions: 1. When compared to sequential treatment, does concurrent chemoradiotherapy increase disease-free survival? 2. What effects does concurrent treatment have on post-operative look, quality of life, and side effects including arm swelling (lymphoedema)? 3. What are each treatment approach's financial costs? Researchers will compare the following to groups: Arm A: Participants in the sequential treatment group will first undergo chemotherapy and then radiation. and Arm B: Participants in the concurrent treatment group will undergo radiation therapy while undergoing chemotherapy. Participants are going to: 1. Get the usual chemotherapy (taxanes and/or anthracyclines). 2. Receive radiation therapy for three to four weeks. 3. Have follow-up visits every 6months for 5years to check for cancer recurrence, side effects, and quality of life.

This description comes directly from the study's public registry record.

Talk to the study team

Tabassum Wadasadawala, MD, DNB Radiotherapy  ·  (+91-22) 24177026  ·  drtabs.radonc@gmail.com

Always discuss trial participation with your own doctor first.

Locations (5)

Homi Bhabha Cancer Hospital & Research CentreVishkhapatnam, Andhra Pradesh, IndiaNot Yet Recruiting
Tata Memorial CentreMumbai, Maharasthra, IndiaRecruiting
Homi Bhabha Cancer Hospital and Research CentreNew Chandigarh, Punjab, IndiaNot Yet Recruiting
Homi Bhabha Cancer Hospital, SangrurSangrur, Punjab, IndiaNot Yet Recruiting
Mahamana Pandit Madan Mohan Malviya Cancer CentreVaranasi, Uttar Pradesh, IndiaNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT06926543