Condition: Sarcopenia in Elderly · Frailty at Older Adults · Functional Capacity · Sponsor: Consorci Sanitari del Maresme
Double-blind randomized placebo-controlled clinical trial with two parallel arms. The main objective is to evaluate the efficacy and safety of creatine supplementation in older adults who have been operated on for total knee arthroplasty and undergoing a usual rehabilitation program. The intervention will consist of daily creatine monohydrate supplementation for 12 weeks. The intervention will start after surgery with a loading dose of 20g/day for 1 week and then continue with a maintenance dose of 5g/day for 11 weeks. Main outcome mesures included muscle mass, muscle strenght, sarcopenia, frailty, functional capacity and physical performance and will be assessed at baseline, 3 and 6 months follow-up.
This description comes directly from the study's public registry record.
Jéssica Martínez Rodríguez · 0034 937417700 · jmartinezro@csdm.cat
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| Elisabet Palomera | Mataró, Barcelona, Spain | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06925880