● Recruiting

A Safety and Efficacy Study Evaluating CTX112 in Adult Subjects With Refractory Autoimmune Disease

Condition: SLE (Systemic Lupus) · Lupus Erythematosus, Systemic · Lupus Nephritis · Sponsor: CRISPR Therapeutics

PhasePhase 1

Planned participants80

Who can joinAll sexes, 18 Years to 70 Years

Healthy volunteersNo

About this study

This is a single-arm, open-label, multicenter, ascending dose Phase 1 study evaluating the safety and preliminary efficacy of CTX112 in adult subjects with refractory autoimmune diseases, including active systemic lupus erythematosus (SLE), systemic sclerosis (SSc), or idiopathic inflammatory myopathy (IIM).

This description comes directly from the study's public registry record.

Talk to the study team

Clinical Trials · 1 877-214-4634 · medicalaffairs@crisprtx.com

Always discuss trial participation with your own doctor first.

Locations (14)

Stanford University Medical Center	Redwood City, California, United States	Recruiting
Northwestern Medicine, Robert H. Lurie Comprehensive Cancer Center	Chicago, Illinois, United States	Recruiting
University of Iowa	Iowa City, Iowa, United States	Recruiting
Manning Family Children's Hospital of New Orleans	New Orleans, Louisiana, United States	Recruiting
Boston Medical Center	Boston, Massachusetts, United States	Recruiting
Washington University School of Medicine	St Louis, Missouri, United States	Recruiting
University of North Carolina TraCS Institute - CTRC	Chapel Hill, North Carolina, United States	Recruiting
University of Augsburg	Augsburg, Germany	Recruiting
Universitätsklinikum Köln	Cologne, Germany	Recruiting
Medizinische Hochschule Hannover (MHH)	Hanover, Germany	Recruiting
UCT University Medical Center Mainz	Mainz, Germany	Recruiting
Research Site 10	Córdoba, Spain	Recruiting

+ 2 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06925542