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Study identifier: NCT06923267 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Ultrasound Evaluation of Cardiac Function During Spontaneous Breathing Trials

Condition: Weaning Invasive Mechanical Ventilation · Weaning-induced Pulmonary Edema · Weaning Failure of Mechanical Ventilation  ·  Sponsor: Centre Hospitalier Régional d'Orléans

PhaseNA
Planned participants24
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this clinical trial is to evaluate the evolution of a cardiac ultrasound index (E/E') during 3 spontaneous breathing trials in Intensive Care Unit (ICU) adults (over 18 years) patients at risk for weaning failure. The main objective is to find out which spontaneous breathing trial is the least demanding in terms of heart work. Investigators will compare 3 consecutive spontaneous breathing trials in a random order to see if one is superior to the others. Participants will not have to perform any specific procedure apart from breathing without respiratory support during the spontaneous breathing trial. During these trials, the investigator will perform cardiac ultrasound measurements.

This description comes directly from the study's public registry record.

Talk to the study team

Guillaume Fossat, Pt, Msc, PhD student  ·  +33238651318  ·  guillaume.fossat@chu-orleans.fr

Elodie Pougoue  ·  +33238744086  ·  elodie.pougoue-touko@chu-orleans.fr

Always discuss trial participation with your own doctor first.

Locations (1)

Chu OrleansOrléans, FranceRecruiting

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Source record: clinicaltrials.gov/study/NCT06923267