Condition: Lung Cancer (NSCLC) · Sponsor: University of Zurich
EBUS-guided cryobiopsy of mediastinal and hilar lymph nodes has shown to be a useful diagnostic tool to obtain tissue for histological analysis and further targeted therapies in lung malignancies. Due to the large size and better quality of the tissue samples, a higher diagnostic yield than with transbronchial needle aspiration (TBNA) can be expected, especially in non-solid tumors. In previous studies different biopsy protocols were used. The freezing time of cryoprobe (which defines the sample sizes) ranged from 3 to 7 s and the number of biopsies was between 1 and 4 samples. It is therefore unclear what freezing times and biopsy frequency are required to obtain the best histological information.
This description comes directly from the study's public registry record.
Carolin Steinack · 0041 44 255 8689 · carolin.steinack@usz.ch
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| Jürgen Hetzel | Basel, Switzerland | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06921681