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Study identifier: NCT06921603 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

POCUS-Guided Diuresis for Decompensated Heart Failure

Condition: Heart Decompensation, Acute · Acute Kidney Injuries  ·  Sponsor: University of Pittsburgh

PhaseNA
Planned participants588
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Heart failure occurs when the heart cannot pump blood effectively, leading to fluid buildup in the body. This can cause problems such as difficulty breathing, swelling, and extreme tiredness. In severe cases, these symptoms worsen to the point where hospitalization is required. Unfortunately, many patients with severe heart failure are readmitted to the hospital within 30 days after discharge, which is both physically and emotionally challenging for patients and places a significant financial burden on individuals and the healthcare system. Although symptoms such as difficulty breathing and swelling may improve during the hospital stay, some patients are discharged with excess fluid remaining in their bodies. This retained fluid often causes symptoms to worsen, leading to subsequent hospital readmissions. Inadequate management of fluid levels can also harm the kidneys, further complicating the patient's condition. This study aims to improve care for heart failure patients by utilizing a simple, non-invasive tool to assess fluid levels more accurately at the bedside. The tool measures the size of a large blood vessel in the neck, providing key information about the pressure inside the heart. This information enables clinicians to determine the appropriate amount of medication needed to remove just the right amount of fluid. Properly managing fluid levels can help prevent kidney damage and improve overall patient outcomes. The primary goal of this study is to evaluate whethe…

This description comes directly from the study's public registry record.

Talk to the study team

John J Pacella, MD  ·  4127805529  ·  pacellajj@upmc.edu

Benay Ozbay, MD  ·  4124502774  ·  benayozbay@hotmail.com

Always discuss trial participation with your own doctor first.

Locations (5)

UPMC EastPittsburgh, Pennsylvania, United StatesNot Yet Recruiting
University of Pittsburgh Medical CenterPittsburgh, Pennsylvania, United StatesRecruiting
UPMC PresbyterianPittsburgh, Pennsylvania, United StatesRecruiting
UPMC MercyPittsburgh, Pennsylvania, United StatesNot Yet Recruiting
UPMC ShadysidePittsburgh, Pennsylvania, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06921603