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Study identifier: NCT06917313 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

FLASH-Breast: Evaluating the Efficacy of Fezolinetant in Reducing Vasomotor Symptoms in Women With Breast Cancer on Endocrine Therapy

Condition: Breast Cancer Early Stage Breast Cancer (Stage 1-3)  ·  Sponsor: Yale University

PhasePhase 2
Planned participants92
Who can joinFemale, 18 Years to no upper limit
Healthy volunteersYes

About this study

This is a phase II, randomized, double-blinded, placebo-controlled trial designed to evaluate the efficacy of fezolinetant (45 mg a day) vs. placebo in reducing moderate to severe vasomotor symptoms (VMS) in breast cancer survivors on endocrine therapy (tamoxifen, aromatase inhibitors). The trial will proceed in a single stage, and the total of 92 participants will be randomized in 1:1 fashion to fezolinetant or placebo arm respectively.

This description comes directly from the study's public registry record.

Talk to the study team

Laura Kane  ·  773-369-6904  ·  laura.kane@yale.edu

Always discuss trial participation with your own doctor first.

Locations (2)

Yale UniversityNew Haven, Connecticut, United StatesRecruiting
The Ohio State University Comprehensive Cancer CenterColumbus, Ohio, United StatesNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT06917313