Condition: Breast Cancer · Breast Cancer, HER2-Expression · Sponsor: The Affiliated Hospital of Qingdao University
This study aims to evaluate the clinical utility of 18F-labeled HER2 Affibody PET for diagnosing and monitoring HER2-expressing breast cancer. HER2, a protein overexpressed in certain malignancies including breast cancer, serves as a critical biomarker for targeted therapies.The HER2 Affibody-an engineered 7 kDa protein with nanomolar affinity for HER2-leverages its rapid tumor penetration and clearance kinetics to achieve high-contrast PET imaging. This study aims to evaluate the diagnostic efficacy of 18F-HER2 Affibody PET in early detection, clinical staging, and treatment response monitoring, thereby providing novel imaging evidence to guide personalized therapeutic strategies for patients with HER2-expressing breast cancer.
This description comes directly from the study's public registry record.
Zhenguang Wang, Doctoral Degree · +86-0532-82913318 · wangzhenguang@qdu.edu.cn
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| Affiliated Hospital of Qingdao University | Qingdao, Shandong, China | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06916637