Condition: Breast Cancer · Sponsor: The Affiliated Hospital of Qingdao University
This study aims to evaluate the diagnostic accuracy (sensitivity, specificity, positive/negative predictive value, and overall accuracy) of 18F-FAPI-04 PET imaging in breast cancer for detecting fibroblast activation protein (FAP)-rich lesions. Additionally, the study will longitudinally monitor dynamic changes in FAP expression levels and tumor size during therapy, including chemotherapy, targeted therapy, or immunotherapy.The non-invasive nature of 18F-FAPI-04 PET addresses limitations of traditional biopsy-dependent stromal evaluation, offering whole-body quantification of tumor microenvironment dynamics to optimize therapeutic decision-making.
This description comes directly from the study's public registry record.
Zhenguang Wang · ＋86-0532-82913318 · wangzhenguang@qde.edu.cn
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| The Affiliated Hospital of Qingdao University | Qingdao, Shandong, China | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06916338