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Study identifier: NCT06915727 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

An Imaging Agent (Pafolacianine) for Identifying Lesions in Pediatric Patients With Primary or Metastatic Solid Tumors

Condition: Childhood Malignant Solid Neoplasm · Childhood Malignant Thoracic Neoplasm · Malignant Abdominal Neoplasm  ·  Sponsor: Mayo Clinic

PhasePhase 3
Planned participants20
Who can joinAll sexes, 6 Months to 17 Years
Healthy volunteersNo

About this study

This phase III trial studies how well pafolacianine works for identifying cancerous lesions in children and adolescent patients with primary solid tumors or solid tumors that have spread from where they first started (primary site) to other places in the body (metastatic). Pafolacianine is a fluorescent imaging agent that targets folate receptors which are overexpressed in many cancers and is used with near infrared (NIR) imaging during surgery to identify tumor cells. NIR uses a special camera that uses wavelengths in the infrared range to visualize and locate the tumor cells that are lit up by the pafolacianine. Giving pafolacianine for NIR imaging may work better than other imaging agents in identifying cancerous lesions in pediatric patients with solid tumors.

This description comes directly from the study's public registry record.

Talk to the study team

Clinical Trials Referral Office  ·  855-776-0015  ·  mayocliniccancerstudies@mayo.edu

Gina Lewis  ·  507-284-0850  ·  DOSCRO2@mayo.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Mayo Clinic in RochesterRochester, Minnesota, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06915727