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Study identifier: NCT06915324 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Transcranial Direct Current Stimulation for Post Treatment Lyme Disease

Condition: Post-Treatment Lyme Disease  ·  Sponsor: Columbia University

PhaseNA
Planned participants110
Who can joinAll sexes, 18 Years to 70 Years
Healthy volunteersNo

About this study

The primary purpose of this pilot study is to investigate a novel approach to the treatment of cognitive symptoms that persist despite prior antibiotic treatment for Lyme disease (Post treatment Lyme Disease or PTLD). Aim 1: The primary aim of this study is to assess whether the processing speed of individuals with PTLD can be enhanced by combining transcranial direct current stimulation (tDCS) with computer based cognitive training games. To achieve this aim, over a 4-week period, all individuals with PTLD will participate in at home adaptive cognitive training combined with either active stimulation or sham stimulation. Aim 2: To determine if treatment benefit in processing speed is sustained, the study will compare the sham and active groups 8 weeks after completion of study treatment.

This description comes directly from the study's public registry record.

Talk to the study team

Mara Kuvaldina, PhD  ·  646-774-8108  ·  mk4480@cumc.columbia.edu

Ellen Brown, BA  ·  646-774-7503  ·  eb3048@cumc.columbia.edu

Always discuss trial participation with your own doctor first.

Locations (2)

University of California, San FranciscoSan Francisco, California, United StatesRecruiting
Columbia University Department of PsychiatryNew York, New York, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06915324