Condition: Primary Liver Cancer · Hepatocellular Carcinoma (HCC) · Cholangiocarcinoma · Sponsor: Maastricht University
The goal of the DRAGON PLC clinical trial is to determine whether portal vein embolization (PVE) combined with hepatic vein embolization (HVE) improves resectability and overall survival in patients with initially unresectable primary liver cancer compared to standard PVE alone. This trial specifically focuses on patients with hepatocellular carcinoma and cholangiocarcinoma. The main questions this trial aims to answer are whether combined PVE and HVE increases the proportion of patients who become resectable within 3 weeks and improves 5-year overall survival compared to PVE alone by enhancing liver hypertrophy. Participants will: * Undergo either standard PVE or combined PVE and HVE. * Have regular imaging to assess liver resectability. * Be monitored for survival outcomes up to 5 years after intervention.
This description comes directly from the study's public registry record.
Fenna A van der Zijden, MSc Technical Medicine · +31640911632 · fenna.van.der.zijden@mumc.nl
Sinead James, MD · +31 638463945 · sinead.james@mumc.nl
Always discuss trial participation with your own doctor first.
| Yale School of Medicine Hospital | New Haven, Connecticut, United States | Not Yet Recruiting |
| Rush University Medical Center | Chicago, Illinois, United States | Not Yet Recruiting |
| Mayo Clinic | Rochester, Minnesota, United States | Not Yet Recruiting |
| Memorial Sloan Kettering Cancer Center | New York, New York, United States | Not Yet Recruiting |
| Cleveland Clinic | Cleveland, Ohio, United States | Not Yet Recruiting |
| Monash Medical Center | Melbourne, Australia | Not Yet Recruiting |
| Medical University of Vienna | Vienna, State of Vienna, Austria | Not Yet Recruiting |
| Social Center South | Vienna, State of Vienna, Austria | Not Yet Recruiting |
| Erasmus Hospital | Brussels, Brussels Capital, Belgium | Not Yet Recruiting |
| UZ Antwerpen | Antwerp, Edegem, Belgium | Not Yet Recruiting |
| UZ Gent | Ghent, Gent, Belgium | Not Yet Recruiting |
| CHU Liège | Liège, Liège, Belgium | Recruiting |
+ 43 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT06914648