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Study identifier: NCT06914557 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Scrambler Therapy With Duloxetine-based Usual Care vs Duloxetine-based Usual Care for Chemotherapy-induced Peripheral Neuropathy.

Condition: CIPN - Chemotherapy-Induced Peripheral Neuropathy · Pain  ·  Sponsor: Fox Chase Cancer Center

PhasePhase 2
Planned participants50
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The investigators hypothesize that Scrambler therapy with duloxetine, compared to duloxetine-based usual care, will result in greater improvement in CIPN as measured by the BPI-Short Form. In addition, the investigators will further assess pain using the EORTC CIPN-20 and determine whether Scrambler therapy results in improved levels of function as measured with the PDQ, and a decreased need for opioid medications. Our primary objective is to investigate whether Scrambler therapy with duloxetine is superior to duloxetine-based usual care in achieving at least a 50% reduction in pain scores, when comparing the cross-sectionally measured "average" pain score at day 35 to the cross-sectionally measured "average" pain score at baseline.

This description comes directly from the study's public registry record.

Talk to the study team

Gerald Nkogbu, MBBS, MS  ·  2157285378  ·  gerald.nkogbu@fccc.edu

Leslie Fortin, MPH  ·  215-214-3996  ·  leslie.fortin@fccc.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Fox Chase Cancer CenterPhiladelphia, Pennsylvania, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06914557