Condition: Preeclampsia (PE) · Hypertensive Disorder of Pregnancy · Sponsor: Heidelberg University
Preeclampsia is a pregnancy-specific hypertensive disorder and can progress rapidly to severe adverse outcomes affecting both the mother and the fetus. Endothelial and microcirculatory dysfunction mediate systemic preeclampsia-related organ dysfunctions. Changes in endothelial and vascular function in preeclampsia have been demonstrated through reduced flow-mediated vasodilation as a result of reduced availability of nitric oxide, which potentially persists up to several years postpartum. Hyperspectral imaging is a new innovative technology that allows to assess the peripheral microcirculation and perfusion non-invasively and contactless, but has never been evaluated in the context of preeclampsia before. This EPICS project (Endothelial dysfunction for Prognosis In patients with preeClampSia) is a prospective observational study and aims to investigate hyperspectral imaging as a new potential diagnostic and prognostic marker in preeclampsia.
This description comes directly from the study's public registry record.
Dr. med. Anna Scholz · +49 6221 56 32080 · anna.scholz@med.uni-heidelberg.de
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| Heidelberg University Hospital, Department of Gynecology and Obstetrics | Heidelberg, Germany | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06912477