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Study identifier: NCT06911450 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Pleural Strain by Speckle-Tracking Ultrasound: Feasibility and Driving Pressure Associations

Condition: Ventilation, Mechanical · ARDS (Acute Respiratory Distress Syndrome)  ·  Sponsor: First Affiliated Hospital of Wannan Medical College

PhaseN/A
Planned participants75
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

What is this study about? This research aims to test a new ultrasound technology called "speckle tracking" to measure how much the lining of your lungs (pleura) stretches during breathing, especially if you're on a breathing machine (ventilator). Doctors want to see if this technology can help them adjust ventilator settings more safely, reducing the risk of lung damage. Why is this important? Lung protection: Patients on ventilators, especially those with severe lung problems (like ARDS or pneumonia), need careful settings. Too much pressure from the ventilator can harm the lungs. Better monitoring: Current tools can't easily measure lung stretching at the bedside. This ultrasound method might offer a simple, painless way to check lung health in real time. Who can join? Included: Adults (18+ years) in the ICU with serious illness (assessed by a standard score called APACHE II \>8), whether on a ventilator or not. Excluded: People with recent chest surgery, broken ribs, nerve/muscle diseases, or pregnancy (to avoid risks and ensure accurate measurements). What will happen during the study? Ultrasound scans: A small probe will be placed gently on your chest for 5-10 minutes. The machine will record videos of your lung movements during breathing. This is painless and uses no radiation. Measurements: Doctors will repeat the scan twice (10 minutes apart) to check consistency. For ventilator patients, scans will be done at different pressure settings to see how lung stret…

This description comes directly from the study's public registry record.

Talk to the study team

Qiancheng Xu  ·  86-18297529106  ·  qianchengxu@wnmc.edu.cn

Always discuss trial participation with your own doctor first.

Locations (1)

The First Affiliated Hospital of Wannan Medical College (Yijishan Hospital of Wannan Medical College)Wuhu, Anhui, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06911450