Condition: ADHD - Attention Deficit Disorder With Hyperactivity · Driving Simulator Performance · ADHD · Sponsor: Stefan Lakämper
Attention deficit hyperactivity disorder (ADHD) or syndrome (ADHS) is a symptomatically defined condition that - if untreated - is linked to a significantly increased risk of traffic accidents. In a recent umbrella review, where data from reviews and meta-analyses on 21.142.129 adults was assessed, a pooled prevalence of 3.1% of ADHD in adults was estimated. Considering that globally around 1.35 million people lose their lives and more than 50 million are suffering from injuries or disabilities due to road accidents, the fraction of car accidents caused by ADHD as a risk factor is considerable and needs to be addressed. This risk is largely presumed to be caused by an elevated level of inattentiveness in affected persons. Compounds of different groups, which can be classified in stimulants - formulations of methylphenidate and amphetamine - and non-stimulants - atomoxetin, guanfacine and clonidine -, have been shown to be effective in alleviating negative effects of ADHD, including inattentiveness. Under well-established but individually managed medication regimes, affected individuals can consequently lead a largely "unirritated" life and are not subject to fundamental restriction with respect to driving anymore. In children and adolescents, documented negative effects of stimulant medication include loss of appetite and decreased growth rates. It could however be shown that short-term interruptions (weekend, school holidays, and alike), introduced to alleviate aforementio…
This description comes directly from the study's public registry record.
Stefan Lakämper, Dr. rer. nat. · +41793789984 · stefan.lakaemper@irm.uzh.ch
Nan Li, MSc · +41797283245 · nan.li@irm.uzh.ch
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| Division of Traffic Medicine, Institute of Forensic Medicine, University of Zurich, | Zurich, ZRH, Switzerland | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06910605