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Study identifier: NCT06909916 Synced from ClinicalTrials.gov · July 29, 2026
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Weight-Bearing CT and Conventional Periprosthetic Distal Knee Fractures

Condition: Periprosthetic Fracture Around Prosthetic Joint Implant  ·  Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

PhaseNA
Planned participants20
Who can joinAll sexes, 50 Years to 90 Years
Healthy volunteersNo

About this study

Total knee arthroplasty (TKA) is a surgical procedure commonly conducted for patients with end-stage knee osteoarthritis, often leading to improved pain relief and function. However, for patients that have suffered an associated periprosthetic fracture, a broken bone that occurs around the implant of a TKA, they may receive sub-optical care due to a lack of a trustworthy assessments for component fixation and fracture healing in the literature. The prevalence of TKA surgeries is increasing annually and is projected to rise further due to an ageing population and obesity issue. By extension to this primary surgery, more Canadians will require an invasive revision surgery that risks patient morbidity and mortality. Thus, it is imperative to set a standard for fixation and bone healing assessments to lessen revision burdens and improve patient outcomes. CT imaging can effectively visualize areas of incomplete bone ingrowth that may be hidden from overlapping anatomy on plain radiographs, which remains the go-to imaging modality for orthopaedic surgeons to assess periprosthetic fracture healing. The purpose of this prospective cross-sectional study is to examine the efficacy of weight-bearing CT as a diagnostic tool for 20 participants who experienced a distal femur periprosthetic fracture and underwent revision surgery using a fracture fixation plate and screws. Participants will be scanned under loaded and unloaded conditions. Radiographic outcomes will be evaluated, including …

This description comes directly from the study's public registry record.

Talk to the study team

Brent Lanting, MD  ·  519-685-8500  ·  brent.lanting@lhsc.on.ca

Farzan Mohammadreza, MSc  ·  5197298079  ·  farzan.mohammadreza@lhsc.on.ca

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Locations (1)

University Hospital - London Health Sciences CentreLondon, Ontario, CanadaRecruiting

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Source record: clinicaltrials.gov/study/NCT06909916