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Study identifier: NCT06909565 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Inclisiran Versus Placebo for the Prevention of Major Adverse Cardiovascular and Limb Events in Patients Undergoing Percutaneous Coronary Intervention or Peripheral Endovascular Intervention

Condition: Percutaneous Coronary Intervention · Peripheral Endovascular Intervention  ·  Sponsor: Duke University

PhasePhase 4
Planned participants6000
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

V-INTERVENTION will evaluate the effectiveness of inclisiran in preventing major cardiovascular and limb events in patients receiving percutaneous coronary or peripheral arterial revascularization. Inclisiran is a subcutaneous, twice-yearly injection that is FDA-approved as an adjunct with statin therapy and on the market to lower LDL-C in high-risk populations.

This description comes directly from the study's public registry record.

Talk to the study team

Robin Barron-Nelson, RN, MSN  ·  321-946-2747  ·  robin.barron-nelson@duke.edu

Jen Holt  ·  +1 919 824 6334  ·  jen.holt@duke.edu

Always discuss trial participation with your own doctor first.

Locations (115)

Advanced Cardiovascular LLCAlexander City, Alabama, United StatesRecruiting
Cardiology, PCBirmingham, Alabama, United StatesRecruiting
Heart Center Research, LLCHuntsville, Alabama, United StatesRecruiting
Cardiology Associates Research GroupJonesboro, Arkansas, United StatesRecruiting
Arkansas CardiologyLittle Rock, Arkansas, United StatesRecruiting
Pacific Oaks Medical GroupBeverly Hills, California, United StatesRecruiting
Cardiovascular Institute of San DiegoChula Vista, California, United StatesRecruiting
Valley Clinical TrialsCovina, California, United StatesWithdrawn
Thrive Clinical Research GroupGlendora, California, United StatesRecruiting
Radin Cardiovascular Medical Group, IncNewport Beach, California, United StatesRecruiting
Valley Clinical Trials, LLC - Flourish ResearchNorthridge, California, United StatesRecruiting
Riverside Community HospitalRiverside, California, United StatesRecruiting

+ 103 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06909565