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Study identifier: NCT06908759 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Risk of Falling and Cardiac Rehabilitation

Condition: Risk of Falling · Elderly (People Aged 65 or More) · Cardiovascular Diseases  ·  Sponsor: IRCCS San Raffaele Roma

PhaseNA
Planned participants150
Who can joinAll sexes, 65 Years to no upper limit
Healthy volunteersNo

About this study

Background and Rationale Cardiac rehabilitation (CR) is a key intervention for patients with chronic heart disease or recent acute cardiovascular events. In elderly and frail patients, CR aims not only to improve functional capacity but also to maintain or recover independence in daily activities. Hospitalization following an acute event often leads to bed rest, which-even after just 2-3 days-can cause hypokinetic syndrome, characterized by loss of muscle tone, orthostatic hypotension, decreased mobility, and psychological decline, including depression. Moreover, immobility increases thrombotic risk and vascular complications. To mitigate these effects, CR is initiated promptly after clinical stabilization and includes three phases: 1. Phase I - In-hospital rehabilitation 2. Phase II - Early outpatient rehabilitation 3. Phase III - Long-term maintenance Elderly patients are particularly vulnerable to falls due to the combined effects of reduced muscle strength, orthostatic hypotension, cognitive decline, and pre-existing sarcopenia-often exacerbated by acute events and immobility. Approximately 60% of cardiac patients hospitalized for acute events present with moderate-to-high fall risk. Fall risk in this population is multifactorial, involving cardiovascular issues (e.g., arrhythmias, orthostatic hypotension), medication effects, and non-cardiac factors such as vision loss, balance impairment, neuromuscular conditions, and cognitive deficits.

This description comes directly from the study's public registry record.

Talk to the study team

Lucia Gatta  ·  +390652253440  ·  lucia.gatta@sanraffaele.it

Always discuss trial participation with your own doctor first.

Locations (1)

IRCCs San RaffaeleRome, RM, ItalyRecruiting

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Source record: clinicaltrials.gov/study/NCT06908759