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Study identifier: NCT06908031 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

SCRT+mFOLFOX6+PD-1 Antibody and Targeted Therapy for High-Risk pMMR/MSS Rectal Cancer(CRIT)

Condition: Rectal Adenocarcinoma · High-Risk Cancer · MSS  ·  Sponsor: Sixth Affiliated Hospital, Sun Yat-sen University

PhasePhase 2
Planned participants49
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

To explore the efficacy and safety of short-course radiotherapy combined with mFOLFOX6, PD-1 monoclonal antibody and cetuximab (for RAS/BRAF Wild-Type)/bevacizumab (for RAS/BRAF Mutant) in High-Risk pMMR/MSS Rectal Adenocarcinoma through a prospective study, providing high-level evidence-based medical evidence for the use in the treatment of high-risk rectal cancer.

This description comes directly from the study's public registry record.

Talk to the study team

Jun Huang, PhD.  ·  +8613926451242  ·  huangj97@mail.sysu.edu.cn

Fang He, MD.  ·  +8618826059789  ·  hefang23@mail.sysu.edu.cn

Always discuss trial participation with your own doctor first.

Locations (1)

Sixth Affiliated Hospital, Sun Yat-sen UniversityGuangzhou, Guangdong, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06908031